The lymphatic system is a large network made up of lymphatic vessels, lymphatic organs, lymphatic tissues and lymph nodes where the primary function is to transport lymph fluid around the body and act as a drainage system. It carries various proteins, fats and hormones to cells and is a key part of the immune system, producing antibodies and white blood cells to help the body fight off infections. Over time unwanted toxins can accumulate in the lymphatic system leading to congestion, imbalances and certain chronic health conditions. By stimulating specific lymphatic drainage points which are connected to the nervous system, this encourages the lymphatic system to flow across the nervous system and throughout the entire body aiding with the detoxification of accumulated and congested toxins, as well as eliminating waste products, alleviating lymphatic pressure in certain areas and reducing overall inflammation in the body. The aim is to ensure that the lymphatic system, nervous system and surrounding tissues and organs regain optimal function and to restore energy flow and balance throughout the body. Over the last few years, Rakhee and her team are seeing an increasing number of patients who present with CFS symptom.

The link between the lymphatic system and the brain was only confirmed to exist in humans in 2017, thus the scientific basis of The Perrin Technique, which suggested that ME/CFS was due to a disturbed neuro-lymphatic system, was almost three decades ahead of its time and initially met with resistance from most scientists and medics worldwide. Now, the neuro-lymphatic (also known as the Glymphatic)
system is recognised as a verified mechanism that drains large molecules and toxins via cerebrospinal fluid into lymphatic vessels lining the brain.

Toxins resulting from infection or inflammation in the head or spine should drain through perforations in a bony plate (the cribriform plate) just above the nasal cavity, as well as other cranial nerve pathways such as the optic and auditory pathways and the trigeminal into the lymph ducts around the eyes, ears, and mouth and down the face and neck. These toxins are also supposed to drain down the spinal cord and into the lymph ducts along the spine. Dr. Perrin has found that these normal drainage points can be structurally damaged due to previous trauma to the head and spine or due to developmental or congenital and hereditary issues that result in structural disturbances in these key areas. Even minor damage can lead to a restriction of healthy drainage, leading to congestion in the  neuro-lymphatic flow, initiating a vicious cycle of neurotoxicity that results in a reversal of lymphatic flow and engorged 'varicose' lymphatic vessels, particularly in the chest and neck.